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Nagaraju, J. and Goldsmith, M.R. (2002) Silkworm genomics - progress and prospects. Current Science, 83 (4). pp. 415-425. ISSN 0011-3891

Curr Sci 83 p415.pdf

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The biology and genetics of silkworm, Bombyx mori, is the most advanced of any lepidopteran species. Its rich repertoire of genetic resources and potential applications in sericulture and as a model for other Lepidoptera led to the initiation of genomics research. During the past decade much effort has been made in the areas of marker development, and molecular maps have been constructed in standard strains with the use of RFLPs, RAPDs, ISSRs, STSs, and microsatellites. The potential applications of molecular markers and linkage maps include stock identification, Marker Assisted Selection (MAS), identification of Quantitative Trait Loci (QTL), and, ultimately, positional cloning of visible mutations and QTL. To these ends, BAC libraries have been constructed and are being used to make large-scale physical maps, with markers based on ESTs as framework anchors. Altogether this work provides a foundation for identification of gene function, gene and chromosome evolution, and comparative genomics.

Item Type: Article
Subjects: Genetics
Depositing User: Dr P Divakar
Date Deposited: 03 Jun 2015 06:36
Last Modified: 07 Oct 2015 08:50
URI: http://cdfd.sciencecentral.in/id/eprint/137

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