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Goulding, C.W. and Apostol, M. and Anderson, D.H. and Gill, H.S. and Smith, C.V. and Kuo, M.R. and Yang, J.K. and Waldo, G.S. and Suh, S.W. and Chauhan, R. and Kale, A. and Bachhawat, N. and Mande, S.C. and Johnston, J.M. and Lott, J.S. and Baker, E.N. and Arcus, V.L. and Leys, D. and McLean, K.J. and Munro, A.W. and Berendzen, J. and Sharma, V. and Park, M.S. and Eisenberg, D.A. and Sacchettini, J. and Alber, T. and Rupp, B. and Jacobs, W. and Terwilliger, T.C. (2002) The TB structural genomics consortium: providing a structural foundation for drug discovery. Current Drug Targets: Infectious Disorders, 2 (2). pp. 121-141. ISSN 1568-0053

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Abstract

Structural genomics, the large-scale determination of protein structures, promises to provide a broad structural foundation for drug discovery. The tuberculosis (TB) Structural Genomics Consortium is devoted to encouraging, coordinating, and facilitating the determination of structures of proteins from Mycobacterium tuberculosis and hopes to determine 400 TB protein structures over 5 years. The Consortium has determined structures of 28 proteins from TB to date. These protein structures are already providing a basis for drug discovery efforts.

Item Type: Article
Depositing User: Dr P Divakar
Date Deposited: 03 Jun 2015 12:06
Last Modified: 10 Dec 2015 08:09
URI: http://cdfd.sciencecentral.in/id/eprint/143

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