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Rekha, T. and Khan, A.A. and Alavi, A. and Hussain, M.A. and Habeeb, A. and Ahmed, N. and Habibullah, C.M. (2003) Genetic fine structure analysis of Helicobacter pylori isolates before and after treatment. Indian Journal of Medical Microbiology, 21 (3). pp. 166-171.

Ind J Med Microbiol 21 p166.pdf

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Eradication of H. pylori infection cures peptic ulcer disease and conversely, relapse is associated with reappearance of H. pylori infection. However, it is not clear whether the recurrence of ulcers following H. pylori eradication is due to recrudescence (identical strain) of the previous infection or as a result of exogenous reinfection (different strain) by another strain. The aim of the present study was to analyze the FAFLP patterns of pre and post treatment H. pylori samples to check if the recurrence was due to recrudescence or reinfection. It can be concluded that in the present series of patients, reinfection was due to recrudescence of infection due to incomplete eradication. The study also suggests that DNA fingerprinting by FAFLP provides discriminatory and complementary data for identifying strains of H. pylori while monitoring therapy

Item Type: Article
Depositing User: Dr P Divakar
Date Deposited: 09 Jun 2015 11:52
Last Modified: 09 Jun 2015 11:52
URI: http://cdfd.sciencecentral.in/id/eprint/162

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