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Yellaboina, S. and Seshadri, J. and Kumar, M.S. and Ranjan, Akash (2004) PredictRegulon: a web server for the prediction of the regulatory protein binding sites and operons in prokaryote genomes. Nucleic Acids Research, 32 (Web Se). W318-W320. ISSN 1362-4962

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Abstract

An interactive web server is developed for predicting the potential binding sites and its target operons for a given regulatory protein in prokaryotic genomes. The program allows users to submit known or experimentally determined binding sites of a regulatory protein as ungapped multiple sequence alignments. It analyses the upstream regions of all genes in a user-selected prokaryote genome and returns the potential binding sites along with the downstream co-regulated genes (operons). The known binding sites of a regulatory protein can also be used to identify its orthologue binding sites in phylogeneticaly related genomes where the trans-acting regulator protein and cognate cis-acting DNA sequences could be conserved. PredictRegulon can be freely accessed from a link on our world wide web server: http://www.cdfd.org.in/predictregulon/.

Item Type: Article
Depositing User: Dr P Divakar
Date Deposited: 25 Jun 2015 11:31
Last Modified: 12 Oct 2015 04:52
URI: http://cdfd.sciencecentral.in/id/eprint/189

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