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Ranjan, Sarita and Yellaboina, S. and Ranjan, Akash (2006) IdeR in Mycobacteria: From Target Recognition to Physiological Function. Critical Reviews in Microbiology, 32 (2). pp. 69-75. ISSN 1040-841X

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Abstract

In mycobacteria, iron dependent transcription regulator (IdeR) regulates transcription of genes in response to iron levels. The IdeR regulated genes have been investigated mostly in M. tuberculosis, M. smegmatis, and in few of the other related species. Recent advances in crystal structure solution and computational as well as experimental identification of IdeR targets has provided insight into IdeR structure and function. Here in this review we take stock of current state of knowledge on IdeR and its targets to understand the underlying design of the IdeR regulon and its role in mycobacterial physiology.

Item Type: Article
Depositing User: Dr P Divakar
Date Deposited: 22 Jul 2015 11:19
Last Modified: 24 Nov 2015 19:43
URI: http://cdfd.sciencecentral.in/id/eprint/284

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