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Ranganath, P. (2015) MicroRNA-155 and its role in malignant hematopoiesis. Biomarker Insights, 10. pp. 95-102. ISSN 1177-2719

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Abstract

MicroRNA-155 (miR-155) is a multifunctional molecule involved in both normal and malignant hematopoiesis. It has been found to be involved in the pathogenesis of many different hematological malignancies with either an oncogenic or a tumor-repressor effect, depending on the nature of the cell and the type of malignancy. In particular, it has been strongly implicated in the causation of diffuse large B-cell lymphomas. This review focuses on the molecular interactions of miR-155, its oncogenic mechanisms, and its potential as an effective therapeutic target for the associated malignancies.

Item Type: Article
Depositing User: Dr P Divakar
Date Deposited: 03 Dec 2015 09:03
Last Modified: 03 Dec 2015 09:03
URI: http://cdfd.sciencecentral.in/id/eprint/686

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