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Singh, Mugdha and Sarkar, A. and Nandineni, M.R. (2018) A comprehensive portrait of Y-STR diversity of Indian populations and comparison with 129 worldwide populations. Scientific Reports, 8. p. 15421. ISSN 2045-2322

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Abstract

India, known for its rich cultural, linguistic and ethnic diversity, has attracted the attention of population geneticists to understand its genetic diversity employing autosomal, Y-chromosomal and mitochondrial DNA markers. Y-chromosomal short tandem repeats (Y-STRs) are useful in understanding population substructures and reveal the patrilineal affinities among populations. Previous studies on Indian populations based on Y-STR markers were either limited to restricted number of markers or focused on few selected populations. In this study we genotyped 407 unrelated male individuals from 12 states in India employing the suite of Y-STRs present in PowerPlex Y23 (Promega, Madison, WI, USA). These populations clustered genetically close to each other irrespective of their geographic co-ordinates and were characterized primarily by R1a, H and L haplogroups. Interestingly, comparison with 129 worldwide populations showed genetic affinity of the Indian populations with few populations from Europe and Levantine. This study presents the first pan-Indian landscape of 23 Y-STRs and serves as a useful resource for construction of an Indian Y-STR database.

Item Type: Article
Depositing User: Dr P Divakar
Date Deposited: 20 Oct 2018 12:25
Last Modified: 20 Oct 2018 12:25
URI: http://cdfd.sciencecentral.in/id/eprint/870

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