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Srivastava, Varsha and Prabhakar Rao, K. and Surekha Rani, H. and Kumawat, R.K. and Mishra, Aditi and Shrivastava, Pankaj (2020) Genomic diversity in the Goud population of Telangana, India inferred using twenty three autosomal marker PowerPlex® Fusion 6C System. Meta Gene, 25. p. 100718. ISSN 2214-5400

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Abstract

With the aim to investigate the genetic diversity of the Goud population of Telangana, India, 121 randomly selected healthy individuals were chosen for this study. The genetic diversity of the studied population was inferred using the PowerPlex® Fusion 6C system. A total of 257 alleles were observed in the studied population, along with the mean number of alleles 11.174 per locus. The locus SE33 showed the maximum number of observed allele i.e., 32, whereas locus TPOX showed the least number of observed allele i.e., 5. The studied population showed a wide range of allele frequencies ranged from 0.004 to 0.442. This wide range of allele frequency showed the diverse nature of the studied population, which is also supported by the broad range of observed Heterozygosity with the minimum value 0.628 to maximum 0.893, suggest the multidirectional gene flow in the studied population. The locus SE33 was also observed as the most polymorphic among all the studied loci. The combined value of the power of discrimination, power of exclusion, paternity index, and matching probability was found to be 1, 0.999999999178452, 9.86 × 108, and 4.5 × 10–28, respectively, for all the studied loci. Neighbor-Joining Tree and Principal Component Analysis (PCA) Plot showed the genetic affinity of the studied population with the Indian, central Indian, and populations of Uttar Pradesh and Jharkhand. This is the first global genetic report of genetic diversity in the Goud population of Telanagana using 23 markers PowerPlex® Fusion 6C system. The obtained genetic data of this study will be useful for forensic application, anthropological, and medical studies.

Item Type: Article
Subjects: Genetics
Depositing User: Dr P Divakar
Date Deposited: 12 May 2020 20:10
Last Modified: 12 May 2020 20:10
URI: http://cdfd.sciencecentral.in/id/eprint/954

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