Majeed, A.A. and Ahmed, N. and Rao, K.R. and Ghousunnissa, S. and Kauser, F. and Bose, B. and Nagarajaram, H.A. and Katoch, V.M. and Cousins, D.V. and Sechi, L.A. and Gilman, R.H. and Hasnain, S.E. (2004) AmpliBASE MTTM: a Mycobacterium tuberculosis diversity knowledgebase. Bioinformatics, 20 (6). pp. 989-992. ISSN 1367-4803

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Abstract

AmpliBASE MTTM is an online databank of high-resolution DNA fingerprints representing fluorescent amplified fragment length polymorphism (FAFLP) profiles or amplitypes developed for the Mycobacterium tuberculosis complex strains from 48 different countries. AmpliBASE MTTM is based on a relational database management system that is hyperlinked to visualize genotyping results in the form of DNA fingerprint images for individual strains. A flexible search system based on systematic comparisons of fragment sizes in base pairs allows inter-laboratory comparison of FAFLP profiles. Besides this, the database also displays previously published data on IS6110 profiles, spoligotypes, MIRU-VNTRs and large sequence polymorphisms along with the FAFLP records that will give the overall comparisons. Being the first of its kind, AmpliBASE MTTM is expected to be a very helpful tool in strengthening the concept of ‘geographic genomics’ and will be very helpful to molecular epidemiologists and those interested in diagnostic development for tuberculosis.

Item Type:	Article
Depositing User:	Users 2 not found.
Date Deposited:	30 Jun 2015 11:26
Last Modified:	30 Jun 2015 11:26
URI:	http://cdfd.sciencecentral.in/id/eprint/204

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