Khosla, Sanjeev and Mendiratta, G. and Brahmachari, V. (2006) Genomic imprinting in the mealybugs. Cytogenetic and Genome Research, 113 (1-4). pp. 41-52. ISSN 1424-8581

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Abstract

The coccid insects (Hemiptera; Sternorrhyncha; Aphidiformes; Coccoidea; Pseudococcidae) are well suited to study not only the mechanisms of genomic imprinting but also facultative heterochromatization, a phenomenon well exemplified by inactivation of the X chromosome in female mammals. Coccids show sex-specific heterochromatization of an entire set of chromosomes and transcriptional silencing of all the paternally contributed chromosomes in males. Thus, genomic imprinting and the resultant differential regulation operate on 50% of the genome in contrast to the single X chromosome in female mammals. A significant insight into the phenomenon of genomic imprinting has come from very elegant cytological analysis of the coccid system. Recently, efforts have been made to dissect out at the molecular level the phenomenon of genomic imprinting in these insects. The present review summarizes both of these aspects. In light of the accruing experimental evidence for chromatin-based differences in the maternal and paternal genomes, it appears that the mealybug system may provide evidence for stable maintenance of chromatin code not only through mitosis but also through meiosis. © 2006 S. Karger AG, Basel

Item Type:	Article
Depositing User:	Users 2 not found.
Date Deposited:	16 Oct 2015 10:23
Last Modified:	31 Aug 2016 07:58
URI:	http://cdfd.sciencecentral.in/id/eprint/554

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