Article

Jha, V. and Pal, Ravi and Kumar, Dhiraj and Mukhopadhyay, Sangita (2020) ESAT-6 Protein of Mycobacterium tuberculosis Increases Holotransferrin-Mediated Iron Uptake in Macrophages by Downregulating Surface Hemochromatosis Protein HFE. The Journal of Immunology, 205 (11). pp. 3095-3106. ISSN 0022-1767

Dolasia, Komal and Nazar, Faiza and Mukhopadhyay, Sangita (2020) Mycobacterium tuberculosis PPE18 protein inhibits MHC class II antigen presentation and B cell response in mice. European Journal of Immunology. ISSN 0014-2980 (In Press)

Jha, V. and Nagender Rao, R. and Janardhan, S. and Raman, Rajeev and Sastry, G.N. and Sharma, Vartika and Subba Rao, J. and Kumar, Dhiraj and Mukhopadhyay, Sangita (2019) Uncovering Structural and Molecular Dynamics of ESAT-6:β2M Interaction: Asp53 of Human β2-Microglobulin Is Critical for the ESAT-6:β2M Complexation. The Journal of Immunology, 203 (7). pp. 1918-1929. ISSN 0022-1767

Srivastava, Shruti and Madhu Babu, B. and Khan, M.Z. and Vinay Kumar, N. and Mukhopadhyay, Sangita (2019) Mycobacterium tuberculosis PPE2 Protein Interacts with p67phox and Inhibits Reactive Oxygen Species Production. Journal of Immunology, 203 (5). pp. 1218-1229. ISSN 0022-1767

Pradhan, Gourango and Abraham, P.R. and Shrivastava, Rohini and Mukhopadhyay, Sangita (2019) Calcium Signaling Commands Phagosome Maturation Process. International Reviews of Immunology, 38 (2). pp. 57-69. ISSN 0883-0185

Udgata, Atul and Dolasia, Komal and Ghosh, Sudip and Mukhopadhyay, Sangita (2019) Dribbling through the host defence: targeting the TLRs by pathogens. Critical Reviews in Microbiology, 45 (3). pp. 354-368. ISSN 1040-841X

Qureshi, R. and Nagender Rao, R. and Madhu Babu, B. and Mukhopadhyay, Sangita (2019) PPE65 of M. tuberculosis regulate pro-inflammatory signalling through LRR domains of Toll like receptor-2. Biochemical and Biophysical Research Communications, 508 (1). pp. 152-158. ISSN 0006-291X

Abraham, P.R. and Devalraju, K.P. and Jha, V. and Valluri, V.L. and Mukhopadhyay, Sangita (2018) PPE17 (Rv1168c) protein of Mycobacterium tuberculosis detects individuals with latent TB infection. PLOS ONE, 13 (11). e0207787. ISSN 1932-6203

Nagender Rao, R. and Singh, Parul and Ghosh, S. and Mukhopadhyay, Sangita (2018) Lipid metabolism and intracellular bacterial virulence: key to next-generation therapeutics. Future Microbiology, 13 (11). pp. 1301-1328. ISSN 1746-0913

Pradhan, Gourango and Shrivastva, Rohini and Mukhopadhyay, Sangita (2018) Mycobacterial PknG Targets the Rab7l1 Signaling Pathway To Inhibit Phagosome–Lysosome Fusion. The Journal of Immunology, 201 (5). pp. 1421-1433. ISSN 0022-1767

Ahmed, Asma and Dolasia, Komal and Mukhopadhyay, Sangita (2018) Mycobacterium tuberculosisPPE18 Protein Reduces Inflammation and Increases Survival in Animal Model of Sepsis. Journal of Immunology, 200 (10). pp. 3587-3598. ISSN 0022-1767

Singh, Parul and Nagender Rao, R. and Ghosh, Sudip and Mukhopadhyay, Sangita (2018) Cell envelope lipids in the pathophysiology of Mycobacterium tuberculosis. Future Microbiology, 13 (6). pp. 689-710. ISSN 1746-0913

Dolasia, Komal and Bisht, M.K. and Pradhan, Gourango and Udgata, Atul and Mukhopadhyay, Sangita (2018) TLRs/NLRs: Shaping the landscape of host immunity. International Reviews of Immunology, 37 (1). pp. 3-19. ISSN 0883-0185

Abraham, P.R. and Pathak, Niteen and Pradhan, Gourango and Latha, G.S. and Mukhopadhyay, Sangita (2017) The N-terminal domain of Mycobacterium tuberculosis PPE17 (Rv1168c) protein plays a dominant role in inducing antibody responses in active TB patients. PLoS One, 12 (6). e0179965. ISSN 1932-6203

Mukhopadhyay, Sangita and Ghosh, Sudip (2017) Mycobacterium tuberculosis: what is the role of PPE2 during infection? Future Microbiology, 12 (6). pp. 457-460. ISSN 1746-0913

Bhat, K.H. and Srivastava, Shruti and Kumar, K.S and Ghosh, S. and Mukhopadhyay, Sangita (2017) The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production. Scientific Reports, 7. p. 39706. ISSN 2045-2322

Udgata, Atul and Qureshi, R. and Mukhopadhyay, Sangita (2016) Transduction of Functionally Contrasting Signals by Two Mycobacterial PPE Proteins Downstream of TLR2 Receptors. The Journal of Immunology, 197 (5). pp. 1776-1787. ISSN 0022-1767

Abraham, P.R. and Udgata, Atul and Latha, G.S. and Mukhopadhyay, Sangita (2016) The Mycobacterium tuberculosis PPE protein Rv1168c induces stronger B cell response than Rv0256c in active TB patients. Infection, Genetics and Evolution, 40. pp. 339-345. ISSN 1567-1348

Singh, Parul and Rao, R.N. and Reddy, J.R.C. and Prasad, R.B.N. and Kumar, K.S. and Ghosh, S. and Mukhopadhyay, Sangita (2016) PE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulence. Scientific Reports, 6. p. 21624. ISSN 2045-2322

Ahmed, A. and Das, A. and Mukhopadhyay, Sangita (2015) Immunoregulatory functions and expression patterns of PE/PPE family members: Roles in pathogenicity and impact on anti-tuberculosis vaccine and drug design. IUBMB Life, 67 (6). pp. 414-427. ISSN 1521-6543

Bhat, K.H. and Mukhopadhyay, Sangita (2015) Macrophage takeover and the host–bacilli interplay during tuberculosis. Future Microbiology, 10 (5). pp. 853-872. ISSN 1746-0913

Sreejit, G. and Ahmed, A. and Parveen, N. and Jha, V. and Valluri, V.L. and Ghosh, S. and Mukhopadhyay, Sangita (2014) The ESAT-6 Protein of Mycobacterium tuberculosis Interacts with Beta-2-Microglobulin (β2M) Affecting Antigen Presentation Function of Macrophage. PLoS Pathogens, 10 (10). e1004446. ISSN 1553-7374

Abraham, P.R. and Latha, G.S. and Valluri, V.L. and Mukhopadhyay, Sangita (2014) Mycobacterium tuberculosis PPE protein Rv0256c induces strong B cell response in tuberculosis patients. Infection, Genetics and Evolution, 22. pp. 244-9. ISSN 1567-7257

Parveen, N. and Varman, R. and Nair, S. and Das, G. and Ghosh, S. and Mukhopadhyay, Sangita (2013) Endocytosis of Mycobacterium tuberculosis Heat Shock Protein 60 Is Required to Induce Interleukin-10 Production in Macrophages. Journal of Biological Chemistry, 288 (34). pp. 24956-24971. ISSN 0021-9258

Bhat, K.H. and Das, A. and Aparna, S. and Mukhopadhyay, Sangita (2013) PPE2 protein ofMycobacterium tuberculosismay inhibit nitric oxide in activated macrophages. Annals of the New York Academy of Sciences, 1283 (1). pp. 97-101. ISSN 0077-8923

Bhat, K.H. and Bhat, A. and Kumar, S. and Sharma, P. and Mukhopadhyay, Sangita (2012) Role of PPE18 Protein in Intracellular Survival and Pathogenicity of Mycobacterium tuberculosis in Mice. PLoS ONE, 7 (12). e52601. ISSN 1932-6203

Bhat, K.H. and Chaitanya, C.K. and Parveen, N. and Varman, R. and Ghosh, S. and Mukhopadhyay, Sangita (2012) Proline-Proline-Glutamic Acid (PPE) Protein Rv1168c of Mycobacterium tuberculosis Augments Transcription from HIV-1 Long Terminal Repeat Promoter. Journal of Biological Chemistry, 287 (20). pp. 16930-16946. ISSN 0021-9258

Mukhopadhyay, Sangita and Nair, S. and Ghosh, S. (2012) Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets. FEMS Microbiology Reviews, 36 (2). pp. 463-485. ISSN 1574-6976

Akhter, Y. and Ehebauer, M.T. and Mukhopadhyay, Sangita and Hasnain, S.E. (2012) The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: Perhaps more? Biochimie, 94 (1). pp. 110-116. ISSN 0300-9084

Mukhopadhyay, Sangita and Balaji, K.N. (2011) The PE and PPE proteins of Mycobacterium tuberculosis. Tuberculosis, 91 (5). pp. 441-447. ISSN 1472-9792

Nair, S. and Pandey, A.D. and Mukhopadhyay, Sangita (2011) The PPE18 Protein of Mycobacterium tuberculosis Inhibits NF- B/rel-Mediated Proinflammatory Cytokine Production by Upregulating and Phosphorylating Suppressor of Cytokine Signaling 3 Protein. The Journal of Immunology, 186 (9). pp. 5413-5424. ISSN 0022-1767

Das, Arghya and Mukhopadhyay, Sangita (2011) The Evil Axis of Obesity, Inflammation and Type-2 Diabetes. Endocrine, Metabolic & Immune Disorders - Drug Targets, 11 (1). pp. 23-31. ISSN 1871-5303

Bashir, N. and Kounsar, F. and Mukhopadhyay, Sangita and Hasnain, S.E. (2010) Mycobacterium tuberculosisconserved hypothetical protein rRv2626c modulates macrophage effector functions. Immunology, 130 (1). pp. 34-45. ISSN 0019-2805

Alam, K. and Ghousunnissa, S. and Nair, S. and Valluri, V.L. and Mukhopadhyay, Sangita (2010) Glutathione-Redox Balance Regulates c-rel-Driven IL-12 Production in Macrophages: Possible Implications in Antituberculosis Immunotherapy. The Journal of Immunology, 184 (6). pp. 2918-2929. ISSN 0022-1767

Nair, S. and Ramaswamy, P.A. and Ghosh, S. and Joshi, D.C. and Pathak, N. and Siddiqui, I. and Sharma, P. and Hasnain, S.E. and Mande, S.C. and Mukhopadhyay, Sangita (2009) The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage. The Journal of Immunology, 183 (10). pp. 6269-6281. ISSN 0022-1767

Tundup, S. and Pathak, Niteen and Ramanadham, M. and Mukhopadhyay, Sangita and Murthy, K.J.R. and Ehtesham, N.Z. and Hasnain, S.E. (2008) The Co-Operonic PE25/PPE41 Protein Complex of Mycobacterium tuberculosis Elicits Increased Humoral and Cell Mediated Immune Response. PLoS ONE, 3 (10). e3586. ISSN 1932-6203

Khan, N. and Alam, K. and Mande, S.C. and Valluri, V.L. and Hasnain, S.E. and Mukhopadhyay, Sangita (2008) Mycobacterium tuberculosisheat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages. Cellular Microbiology, 10 (8). pp. 1711-1722. ISSN 1462-5814

Khan, N. and Alam, K. and Nair, S. and Valluri, V.L. and Murthy, K.J.R. and Mukhopadhyay, Sangita (2008) Association of Strong Immune Responses to PPE Protein Rv1168c with Active Tuberculosis. Clinical and Vaccine Immunology, 15 (6). pp. 974-980. ISSN 1556-6811

Hussain, M.A. and Naveed, S.A. and Sechi, L.A. and Ranjan, Sarita and Alvi, A. and Ahmed, I. and Ranjan, Akash and Mukhopadhyay, Sangita and Ahmed, N. (2008) Isocitrate Dehydrogenase of Helicobacter pylori Potentially Induces Humoral Immune Response in Subjects with Peptic Ulcer Disease and Gastritis. PLoS ONE, 3 (1). e1481. ISSN 1932-6203

Khan, N. and Ghousunnissa, S. and Jegadeeswaran, S.M. and Thiagarajan, D. and Hasnain, S.E. and Mukhopadhyay, Sangita (2007) Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF- B-dependent pathway. International Immunology, 19 (4). pp. 477-486. ISSN 0953-8178

Boddupalli, C.S. and Ghosh, S. and Rahim, S.C. and Nair, S. and Ehtesham, N.Z. and Hasnain, S.E. and Mukhopadhyay, Sangita (2007) Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-rel. Free Radical Biology and Medicine, 42 (5). pp. 686-697. ISSN 0891-5849

Mukhopadhyay, Sangita and Nair, S. and Hasnain, S.E. (2007) Nitric Oxide: Friendly Rivalry in Tuberculosis. Current Signal Transduction Therapy, 2 (2). pp. 121-128. ISSN 1574-3624

Khan, N. and Rahim, S.S. and Boddupalli, C.S. and Ghousunnissa, S. and Padma, S. and Pathak, Niteen and Thiagarajan, D. and Hasnain, S.E. and Mukhopadhyay, Sangita (2006) Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-rel translocation to the nucleus through activation of calmodulin protein. Blood, 107 (4). pp. 1513-1520. ISSN 0006-4971

Silswal, N. and Singh, A.K. and Aruna, B. and Mukhopadhyay, Sangita and Ghosh, S. and Ehtesham, N.Z. (2005) Human resistin stimulates the pro-inflammatory cytokines TNF-α and IL-12 in macrophages by NF-κB-dependent pathway. Biochemical and Biophysical Research Communications, 334 (4). pp. 1092-1101. ISSN 0006-291X

Rahim, S.S. and Khan, N. and Boddupalli, C.S. and Hasnain, S.E. and Mukhopadhyay, Sangita (2005) Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor. Immunology, 114 (3). pp. 313-321. ISSN 0019-2805

Ghosh, S. and Rasheedi, S. and Rahim, S.S. and Banerjee, S. and Choudhary, R.K. and Chakhaiyar, P. and Ehtesham, N.Z. and Mukhopadhyay, Sangita and Hasnain, S.E. (2004) Method for enhancing solubility of the expressed recombinant proteins in Escherichia coli. BioTechniques, 37 (3). 418, 420, 422-433. ISSN 0736-6205

Mukhopadhyay, Sangita and Srivastava, V.M.L. and Murthy, P.K. and Hasnain, S.E. (2004) Poorer NF-κB signaling by microfilariae in macrophages from BALB/c mice affects their ability to produce cytotoxic levels of nitric oxide to kill microfilariae. FEBS Letters, 567 (2-3). pp. 275-280. ISSN 0014-5793

Choudhary, R.K. and Mukhopadhyay, Sangita and Chakhaiyar, P. and Sharma, N. and Murthy, K.J.R. and Katoch, V.M. and Hasnain, S.E. (2003) PPE Antigen Rv2430c of Mycobacterium tuberculosis Induces a Strong B-Cell Response. Infection and Immunity, 71 (11). pp. 6338-6343. ISSN 0019-9567

Bashyam, M.D. and Mukhopadhyay, Sangita (2003) [Book Review] 1. Status of Tuberculosis in India 2. Trends in Malaria and Vaccine Research: The Current Indian Scenario. Infection, Genetics and Evolution, 3 (1). pp. 75-77. ISSN 15671348

Ghosh, S. and Singh, A.K. and Aruna, B. and Mukhopadhyay, Sangita and Ehtesham, N.Z. (2003) The genomic organization of mouse resistin reveals major differences from the human resistin: functional implications. Gene, 305 (1). pp. 27-34. ISSN 0378-1119